| Pro | Francis | Gleeson | Rookie cop in the 41st Precinct of the NYPD |
| | Brian | Stanhope | Francis's partner |
| | Patsy | | Francis's uncle, barkeeper |
| | Anne | Stanhope | Brian's wife |
| | Lena | Teobaldo | Francis's fiancé |
| | | Jaffe | Police sergeant |
| 1 | Karolina | | Lena's cousin |
| | Karol | Teobaldo | Lena's brother |
| | Natusia | Teobaldo | Lena's sister |
| | Angelo | Teobaldo | Lena's father |
| | Gosia | Teobaldo | Lena's mother |
| | Natalie | Gleeson | Francis & Lena's first daughter |
| | Sara | Gleeson | Francis & Lena's 2nd daughter |
| | Peter | Stanhope | Brian & Anne's son |
| | Kate | Gleeson | Francis & Lena's 3rd daughter |
| 2 | Mrs. | Duvin | Peter's 6th grade teacher |
| | Jessica | D'Angelis | One of Peter & Kate's classmates |
| | Lisa | Gordon | One of Peter & Kate's classmates |
| | John | Dills | One of Peter & Kate's classmates |
| | Mr. | Maldonado | One of the neighbors |
| | Mr. | O'Hara | One of the neighbors |
| 3 | Mrs. | Wortham | Customer in Food King store, works at the podiatrist's office |
| | Johnny | Murphy | Customer at Food King store, former high school baseball star |
| | Chris | Smith | One of Peter's classmates |
| | Mr. | Smith | Chris' grandfather |
| | Officer | Dulley | Police officer called to the scene at the Food King store |
| 4 | Joey | Maldonado | One of Peter & Kate's classmates |
| | Sean | Barnett | One of Peter & Kate's classmates |
| | Laura | Fumagalli | One of Peter & Kate's classmates |
| | George | Stanhope | Peter's uncle, his father's brother |
| | Brenda | Stanhope | George's wife, Peter's aunt |
| | Deacon & Mrs. | Gallagher | Sex-ed teachers at Peter & Kate's school |
| 5 | Mrs. | O'Connor | Teacher at Peter & Kate's school |
| | Mr. | Schiavone | Gym teacher at Peter & Kate's school |
| 6 | Mrs. | Quirk | Science teacher from Peter's old school (St. Bart's) |
| | Rohan, Drew, Matt | | Peter's
classmates at Dutch Kills Preparatory High School |
| | Barry | Dillon | Teammate of Peter's on the track team |
| 7 | Dana | | Daughter in the family who bought the Stanhope's house |
| | Vincent | O'Grady | Student who gave the valedictory speech at the high school graduation when Peter was not available |
| 8 | Mr. | Behan | One of Kate's teachers in high school |
| | Marie | Halladay | One of Kate's school friends in high school |
| | Amy | | Kate's friend & fellow camp counselor, soccer teammate |
| | Eddie | Marik | A senior in high school who becomes Kate's boyfriend |
| 9 | Coach | Bell | Peter's track coach at Dutch Kills Prep |
| 10 | Joan | Kavanaugh | Mother of Casey, one of Kate's classmates |
| 11 | Coach | | Peter's college track coach at Elliott College |
| 12 | Dr. | Abbasi | Anne's new doctor at Capital District
Psychiatric Hospital |
| | Margaret | | Director of the Eirene Halfway House |
| | Nancy | | Anne' social worker |
| | Dr. | Oliver | Anne's new doctor |
| 14 | Rosaleen | | George's girlfriend |
| | Dr. | Lehrer | Criminalist in the NYPD who interviewed Kate |
| 15 | Mr. | Kilcoyne | Neighbor of Anne's in Ireland when she was young |
| | Bridget | | Anne's friend when she lived in England |
| | Bernadette | | Anne's younger sister |
| 16 | Frankie | Stanhope | Peter & Kate's son |
| | Molly | Stanhope | Peter & Kate's daughter |
| 17 | Benny | | Peter's police union rep |
| 18 | Sara | | One of Kate's friends, lives in Westchester |
| | Mrs. | Paulino | 1st floor neighbor of George & Rosaleen |
| 19 | Marisol | | Worker at the rehab center to which Peter went |
| 20 | Robbie | | Head history dept. at school where Peter took teaching position |
| 22 | Mr. | Diviny | Lawyer, friend of Brian |
| | Suzie | | Brian's partner in his later years |
