| 1 | Madeleine | Zott | Elizabeth's daughter. |
| | Elizabeth | Zott | Madeline's mother. A research chemist. |
| 2 | Amanda | Pine | Madeline's schoolmate. |
| | Walter | Pine | Amanda's father. |
| | Lyndon | Johnson | The current Vice President. |
| | Calvin | Evans | The star scientist of Hasting Institute. Elizabeth's live-in partner. |
| | Frederick | Sanger | A British chemist that Calvin helped. |
| | Deirdre | | Calvin's ex-lover. Aka: Debbie. |
| | Donatti | | Elizabeth's boss. |
| | Dr. | Meyers | Elizabeth's advisor. |
| | Phillip | | Meyer's top research assistant. |
| 5 | John | Zott | Elizabeth's brother. |
| 6 | Eddie | | One of the geologists. |
| | Miss | Frask | A secretary. Eddie's girlfriend. |
| | Margaret | | Elizabeth's friend. |
| | Peter | Dickman | Margaret's
fiancé. |
| 7 | Six-Thirty | | Elizabeth's dog. |
| | Jack | LaLanne | The famous T.V. guru. |
| 8 | Dr. | Mason | The men's team captain. |
| 11 | Dr. | Boryweitz | Elizabeth's colleague. |
| 17 | Harriet | Sloane | Elizabeth's neighbor. |
| | Dr. | Spock | Elizabeth's doctor. |
| 21 | Mrs. | Mudford | Madeleine's
teacher. |
| | Wakely | | Calvin's schoolmate who became a minister. |
| 24 | Phil | Lebensmal | Walter's boss. The KCTV's executive producer. |
| 25 | Rosa | | The hairdresser. |
| 27 | Judy | | One of Madeleine's classmates. |
| | Mrs. | Fillis | One of the audience. |
| | George | Fillis | Mrs. Fillis's husband. |
| 33 | Edna | Flattistein | The woman who asked Elizabeth about God. |
| | Francine | Luftson | One of Elizabeth's fans. |
| 34 | Mr. | Wilson | Avery's lawyer. |
| | Avery | Parker | The owner of Parker Foundation. Calvin's mother. |
| 35 | Seymour | Browne | Elizabeth's colleague. |
| 36 | Franklin | Roth | An award-winning journalist. |
| 39 | Stella | Pajunas | The world's fastest typist. |