| | | | 2015 Jo |
| | Josette | Kaufman | Ken's daughter. Aka: Jo. |
| | Lila | | Jo's youngest daughter. |
| | Kim | | Jo's eldest daughter. |
| | Melissa | | Kim's sister. aka: Missy. |
| I | | | 1950 Jo |
| | Kalman | Kaufman | Sarah's husband. Aka: Ken. |
| | Sarah | | Jo's mother. |
| | Elizabeth | Kaufman | Jo's sister. aka: Bethie. |
| | | | Bethie |
| | Zayde | | Sarah's father. |
| | Mae | | A housekeeper. |
| | Frieda | | Mae's daughter. |
| | Bubbe | | Zayde's wife. |
| | | | Jo |
| | Iris 1 | | Kaufman's new maid. |
| | Sheila | | One of Kaufman's neighbors. |
| | Claire | | One of Kaufman's neighbors. |
| | Joe | Ginsberg | A player. |
| | | | Bethie |
| | Stan | Danovich | A meat shop owner. |
| | Mr. | Tartaglia | Bethie's acquaintance. |
| | Miss | Keyes | Bethie's teacher. |
| | Mrs. | Lambert | A music teacher. |
| | Cheryl | Goldfarb | A 6th grade student who played the role of Queen Esther. |
| | Barbara | Simoneaux | Bethie's best friend. |
| | Mrs. | Jacobs | A teacher. |
| | Donald | Gitter | The narrator. |
| | Mr. | Goldfarb | Cheryl's father. |
| | | | Jo |
| | Lynette | Bobeck | Jo's friend. Aka: Lynnie. |
| | Bobby | Carver | A football team captain. |
| | LaDonna | Moore | Jo's friend. |
| | LaDrea | Moore | LaDonna's twin sister. |
| | Vernita | Clinkscale | Jo's basketball teammate. |
| | Mrs. | Bobeck | Lynette's mother. |
| | Carla | | A camp counselor. |
| | Leonard | Weiss | Jo's boyfriend. Aka: Len. |
| | Stan | | One of Jo's acquaintances. |
| | Donald 1 | | One of Jo's acquaintances. |
| | Paul | | One of Jo's acquaintances. |
| | | | Bethie |
| | Donald | Powers | The student council treasurer. |
| | Laura | Ochs | One of Bethie's friends. |
| | Darlene | Conti | One of Bethie's friends. |
| | Elkie | | Ken's mother. |
| | Melvin | | Ken's brother. Aka: Mel. |
| | Shirley | | Ken's wife. |
| | Audrey | | One of Shirley's daughters. |
| | Joanne | | One of Shirley's daughters. |
| | Donald 2 | | Shirley's son. |
| | Chaim | Kaufman | Ken's father. |
| | Patti | Jamison | Bethie's friend. |
| | Larry | Fein | Bethie's cousin. |
| | Kaye | Greenfield | Bethie's friend. |
| | Henry | Sheshevsky | Ken's friend. |
| | Andy | Simoneaux | Barbara's brother. |
| | Coralee | | A maid. |
| | | | Jo |
| | Mrs. | Douglas | A teacher. |
| | Allan | Gross | One of Jo's acquaintances. |
| | Louis | Ettinger | One of Jo's acquaintances. |
| | Beth | | Laura's roommate. |
| | | | Bethie |
| | Winnie | Freed | Bethie's acquaintance. |
| | Dr. | Sachs | A pediatrician. |
| | Denise | | One of Bethie's acquaintances. |
| | Suzanne | | One of Bethie's acquaintances. |
| | Mr. | Blundell | A Math teacher. |
| | Miss | McCullough | A drama teacher. |
| | Harold | Jefferson | The star player of the football team. |
| | Carl | Berringer | Drama's lead actor. |
| | Doodie | Sanders | In-charge of props and costumes. |
| | Lynn | Friedlander | Doodie's companion. |
| | | | Jo |
| | Don | Stein | Sarah's neighbor. |
| | Beverly | | Don's wife. |
| | Tim 1 | | One of Beverly's kids. |
| | Pat | | One of Beverly's kids. |
| | Donald Jr. | | One of Beverly's kids. |
| | Mr. | Simoneaux | Barbara's father. |
| | Mrs. | Simoneaux | Barbara's mother. |
| | Randy | Bobeck | One of Lynette's brothers. |
| | Gary | Bobeck | One of Lynette's brothers. |
| | Mrs. | Lyons | Sarah's boss. |
| | Toby | Pettigrew | A former seamstress. |
| II | | | 1962 Bethie |
| | Mrs. | Miller | Bethie's teacher. aka: Killer Miller. |
| | Linda | | Bethie's friend. |
| | Dough | Fitzgibbons | One of Harold's friends. Aka: Dougie. |
| | Devon | Brady | One of Harold's friends. Aka: Dev. |
| | Mr. | Douglass | The vice Principal. |
| | | | Jo |
| | Rochelle Elise | Finkelbein | Jo's friend. Aka: Shelley |
| | Professor | Glass | Jo's teacher. |
| | Rachel | | Jo's friend. |
| | Professor | Fleiss | One of Jo's teacher. |
| | Harlan | Hatcher | The president of the University of Michigan. |
| | Norma | Tester | Jo's classmate. |
| | Doug | Brodesseur | The host of the executive meeting committee. |
| | Marian | Leight | Doug's friend. |
| | Valerie | Moore | Marian's friend. |
| | Dolores | | Shelley's cleaning lady. |
| | Davis | | A driver. |
| | Trish | | Dolores's daughter. |
| | Leo | | Shelley's father. |
| | Gloria | | Shelley's mother. |
| | Dennis | Ziskin | Shelley's boyfriend. Aka: Denny. |
| | | | Bethie |
| | Connie | | One of Bethie's friends. |
| | Flip | | One of Bethie's friends. |
| | Ellen | | One of Sarah's sisters. |
| | Iris 2 | | One of Sarah's sisters. |
| | Max | | Ellen's husband. |
| | Jerry | | One of Ellen's sons. |
| | Alan | | One of Ellen's sons. |
| | Melinda | | Devon's sister. |
| | Randy | | Devon's friend. |
| | Sky | | Scout's little son. |
| | Scott | | Devon's friend. Aka: Scout. |
| | Bonnie | | Scout's wife. Aka: Blue. |
| | Joan | Baez | Bethie's acquaintance. |
| | | | Jo |
| | Professor | Klaas | Jo's teacher. |
| | Donna | | Professor Klaas's research assistant. |
| | Tom | | One of Shelley's brothers. |
| | Pete | | One of Shelley's brothers. |
| | Morrie | | Leo's friend. |
| | Bev | | Morrie's wife. |
| | Leah | | Bev's daughter. |
| | Richard | | Leah's brother. |
| | Katherine | | One of Jo's new friends. Aka: Kat. |
| | Melinda | | One of Jo's new friends. |
| | Gina | | One of Jo's new friends. |
| | | | Bethie |
| | Mrs. | Johnson | Sarah's new neighbor. |
| | Mrs. | Sloan | A teacher. |
| | Mr. | Breedlove | A store manager. |
| | Terrie | | One of Bethie's co-workers. |
| | Marcy | | One of Bethie's co-wokers. |
| | Liz | | One of Bethie's co-workers. |
| | Mrs. | Breedlove | Mr. Breedlove's wife. |
| | | | Jo |
| | Julie | | Denny's sister. |
| | David | Braverman | Shelley's friend. Aka: Dave. |
| | Bingo | | Dave's dog. |
| | Phil | Ochs | David's acquaintance. |
| | Roger | | Dave's fraternity brother. |
| | Danny | | Dave's older brother. |
| | Gigi | | A name of the bar. |
| | Cal | | Jo's acquaintance. |
| III | | | 1974 Bethie |
| | Dr. | Levin | A dentist. |
| | Jeffrey | | A hairdresser. |
| | Drew | van Leer | A band member. |
| | Larry | Krantz | Laura's date. |
| | Ronald | Pearlman | Andy's freshman-year roommate. |
| | Art | Lipkins | Andy's friend. |
| | Suzanne | Loeb | Art's girlfriend. |
| | Ronnie | | A healer. |
| | Wren | | One of Bethie's acquaintances. |
| | Danielle | | One of Bethie's acquaintances. |
| | Kari | | One of Bethie's acquaintances. |
| | Jodi | | One of Bethie's acquaintances. |
| | Sharon | | One of Bethie's acquaintances. Aka: Rose of Sharon |
| | Talia | | One of Bethie's acquaintances. |
| | | | Jo |
| | Francis | | Bethie's acquaintance. |
| | Judy | Pressman | One of Jo's friends. |
| | Stephanie | Zelcheck | One of Jo's friends. |
| | Nonie | Scotto | One of Jo's friends. |
| | Amy | | Nonie's baby. |
| | Drew | | Nonie's son. |
| | Arlene | Dubin | Jo's neighbor. |
| | Mark | Shanley | A lawn mower. |
| | Jenny | Pressman | Judy's daughter. |
| | Mike | | Stephanie's husband. |
| | Lucas | | Stephanie's baby. |
| | George | Toddhunter | A bar manager. |
| | Gus | | A bartender. |
| | Valerie | Cohen | Jo's neighbor. |
| | Dan | | Nonie's huband. |
| | Arnold | | Valerie's husband. |
| | | | Bethie |
| | Margot | | A teacher in an experimental free school. |
| | Derek | | Bethie's acquaintance. |
| | Robert | | A public defender. |
| | Sally | | Bethie's acquaintance. |
| | Philip | | Talia's husband. |
| | Indigo | | One of the children in the Blue Farm Hill. |
| | Marigold | | One of the children in the Blue Farm Hill. |
| | Sasha | | One of the children in the Blue Farm Hill. |
| | | | Jo |
| | Dora | | A name Dave's to call to their third child. |
| | Doris | | Dave's mother. |
| | | | Bethie |
| | Coleman | Young | Detroit's mayor. |
| | James | | Harold's brother. |
| | Hatti | | Harold's sister. |
| | Bernard | | Hatti's husband. |
| | Ernestine | | Harold's sister. aka: Ernie. |
| IV | | | 1987 Bethie |
| | Marge | | One of Sarah's friends. |
| | Carol | | One of Sarah's friends. |
| | Freddie | Barash | A lawyer. |
| | Allison | Shoemaker | A theraphist. |
| | Irene | | Harold's mother. |
| | | | Jo |
| | Richie | Barnes | The director of the recreation department. |
| | Ruthann | Bremmer | One of Jo's students in fitness class. |
| | Connie | McSorley | One of Jo's students in fitness class. |
| | Mr. | Genova | A tech teacher. |
| | Julie | Cardens | Jo's acquaintance. |
| | Derek | Rudolph | Kim's date. |
| V | | | 1993 Bethie |
| | Beverly | Husner | A media coach. |
| | Luke | | Sharon's son. |
| | Jonah | | Luke's brother. |
| | Annie | | Sharon's daughter. |
| | Sidney | | A cook. |
| | Isobel | | A housekeeper. |
| | Alex | | One of the boys Lila babysat. |
| | Meghan | | Alex's sister. |
| | Eileen | Salter | Alex's mother. |
| | Bill | | Eileen's husband. |
| | | Beasley | A police officer. |
| | | | Jo |
| | Amy | Seligson | Lila's only friend. |
| | Ellen | Leong | A therapist. |
| | Mrs. | Futterman | One of the ladies in the fitness class. |
| | Mary Ellen | Weems | A lawyer. |
| | Robert | Rhodes | A NYC lawyer. |
| VI | | | 2006 Jo |
| | Dr. | Mellors | Jo's physician. |
| | Matt | | Kim's husband. |
| | Leonie | | Kim's daughter. |
| | Lester | Shaub | One of the most famous editors in America. |
| | Flora | | Kim's older daughter. |
| | Sandra | Grissom | Matt's mother. Aka: Mimi. |
| | Mirasol | | Flora's nurse. |
| | Taylor | | One of the children Lila babysat. |
| | Alexa | | One of the children Lila babysat. |
| | Zack | | One of the children Lila babysat. |
| | Isla | Clare | A writer. |
| VII | | | 2022 Bethie |
| | Tim 2 | | Lila's son. |
