1 | Aureliano | Buendia Jr. | The colonel. Ursula and Jose Arcadio's son. |
| Melquiades | | The traveling gypsy responsible for showing the inhabitants of Macondo. |
| Jose Arcadio | Buendia | The founder of Macondo. Aureliano's brother. |
| Ursula | Iguaran | Jose's wife. |
| Aureliano | Buendia Sr. | Jose Arcadio's grandfather. |
| Jose Arcadio | Buendia Jr. | Jose Arcadio's first-born son. |
| Francis | Drake | An English Naval officer. A pirate. |
2 | Prudencio | Aguilar | Jose's rival. |
| Pilar | Ternera | Jose Arcadio Jr's wife. |
| Amaranta | Buendia | Ursula and Jose's daughter. |
3 | Arcadio | | Jose Arcadio and Pilar Ternera's son. |
| Rebeca | | The orphan girl. The girl adopted by the Buendia family. Jose Arcadio's wife. |
| Nicanor | Ulloa | Rebeca's father. Jose Sr's friend. |
| Rebeca | Montiel | Rebeca's mother. |
| Cataure | | The Indian man. |
| Francisco | The Man | The song composer in Macondo. |
| Walter | Raleigh | An English writer. |
| Apolinar | Moscote | The magistrate. |
| Amparo | Moscote | Apolinar's daughter. |
| Remedios | Moscote | Apolinar's daughter. Colonel Aureliano's wife. |
4 | Pietro | Crespi | An Italian expert. Amaranta and Rebeca's piano tutor. |
| Aureliano | Jose | Pilar and Colonel Aureliano's son. |
| Magnifico | Visbal | Aureliano's close friend. |
| Gerineldo | Marquez | Aureliano's close friend. |
| Catarino | | A shop owner in Macondo. |
5 | Nicanor | Reyna | The priest who performed the wedding ceremony of Aureliano and Remedios. |
| Alirio | Noguera | Colonel Aureliano's friend. A doctor. |
| Victorio | Medina | The revolutionary general. |
| Bruno | Crespi | Pietro's younger brother. |
| Gregorio | Stevenson | A colonel. |
| Santa Sofia | De La Piedad | Arcadio's wife. |
| Roque | Carcinero | The captain. |
7 | Jose Arcadio | Segundo | Son of Sofia and Arcadio. |
| Remedios | The Beauty | Sofia and Arcadio's daughter. |
| Aureliano | Segundo | Jose Arcadio's twin. |
| Argenida | | Rebeca's servant. |
8 | Visitacion | | Cataure's brother. |
| Jose Raquel | Moncada | The conservative general. The mayor of Macondo. |
| Father | Coronel | The new priest at Macondo. Aka: The Pup. |
| Don Melchor | Escalona | The school head. |
| Aquiles | Ricardo | The commander of the Garrison. |
| Carmelita | Montiel | A fortune card teller. |
9 | Teofilo | Vargas | A liberal leader. |
10 | Fernanda | Del Carpio | Aureliano Segundo's wife. |
| Jose Arcadio | II | Aureliano and Fernanda's son. |
| Antonio | Isabel | The successor of the pup. |
| Petronio | | The sickly sexton. |
| Petra | Cotes | Aureliano Segundo's concubine. |
11 | Renata | Remedios | Fernanda and Aureliano's daughter. Aka: Meme. |
| Aureliano | Triste | One of Colonel Aureliano's illigitimate sons. |
| Aureliano | Centeno | Aureliano Triste's brother. |
12 | Mr. | Herbert | A hot air balloonist. |
| Mr. | Brown | A circus performer. |
13 | Supreme | Pontiff | The languid apprentice. |
| Camila | Sagastume | Aureliano Segundo's opponent in the eating contest. |
14 | Patricia | Brown | One of Meme's friends. |
| Mauricio | Babilonia | Meme's lover. |
15 | Lorenzo | Gavilan | A colonel in the Mexican Revolution. |
| Carlos | Cortes-Vargas | The general commander. |
| Enrique | Garcia-Isaza | The major. Vargas's secretary. |
16 | Amaranta | Ursula | Meme's sister. Fernanda and Aureliano Segundo's daughter. |
17 | Aureliano | Babilonia | Babilonia and Meme's son. |
18 | Aureliano | Amador | One of Colonel Aureliano's
illegitimate sons. |
19 | Gaston | | Ursula's husband. |
| Nigromanta | | Aureliano Babilonia's mistress. |
| Alvaro | | An Arguer. Aureliano Babilonia's friend. |
| German | | An Arguer. Aureliano Babilonia's friend. |
| Alfonso | | An Arguer. Aureliano Babilonia's friend. |
| Gabriel | | An Arguer. Aureliano Babilonia's friend. |
20 | Catalonian | | A bookstore owner in Macondo. |
| Aureliano III | | The dead child of Amaranta Ursula and Aureliano Segundo. |