| Harry | Ames | May Dodd's live-in-partner. |
| Abbott | Anthony | A Benedictine's anchorite. |
| Martha | Atwood | May Dodd's good friend. |
| Monsieur | Audubon | An American ornithologist, naturalist, and painter. |
| Louis | Baptiste | Frenchman who owned trading post. Aka: Big Nose Little Man. |
| Mr. | Benton | A recruiter. |
| Marie | Blanche | May's acquaintance. |
| John G. | Bourke | Captain, Third Cavalry, USA. |
| Madame | Bouvier | May's childhood tutor. |
| Coronel | Bradley | The senior Army officer. |
| Lydia | Bradley | Captain Bourke's fiance. |
| Amos | Chapman | An interpreter. |
| Wesley | Chestnut | Former husband of Daisy Lovelace. |
| W.P. | Clarke | Lieutenant who prepared the pamphlet for signed language. |
| George | Crook | A US Army General. |
| | Crowley | A nurse. |
| General | Custer | An Army officer-in-charge of the expedition. |
| May | Dodd | Formerly a patient in the Lake Forest Lunatic Asylum. |
| Will | Dodd | William's grandson. |
| Jules | Escoffey | The proprietor of a trading post at Camp Robinson. |
| Gretchen | Fathauer | May's friend. |
| Helen Elizabeth | Flight | May's acquaintance. |
| Julia | Grant | Former First Lady of the United States. |
| Ulysses S. | Grant | 18th U.S. President. |
| Ann | Hall | May's companion and collaborator. |
| Reverend | Hare | A corpulent Episcopal missionary. |
| Captain | Henely | U.S. Naval officer. |
| Lieutenant | James | A military officer. |
| Sara 1 | Johnstone | One of May's acquaintances. |
| Sidney | Kaiser | The hospital's chief physician. |
| Margaret | Kelly | One of May's acquaintances. Aka: Meggie. |
| Susan | Kelly | Margaret's twin sister. Aka: Susie. |
| Fern | Louise | Daisy's dog. |
| Daisy | Lovelace | One of May's acquaintances. |
| Ranald S. | Mackenzie | United States Army officer and general in the Union Army. |
| Mrs. | Mallory | Owner of a boarding house. |
| Gertie | McCartney | Real name of Jimmy. Aka: a Dirty Gertie. |
| Cyrus | McCormick | Invented the reaper. |
| Jeannette | Parker | A professional seamstress. |
| Levi | Robinson | A lieutenant who was ambushed and murdered. |
| Jules | Seminole | A man married to the chief's niece. |
| William | Shakespeare | An English playwright, poet, and actor. |
| General | Sheridan | U.S. Army officer. |
| Coronel | Smith | A military officer. |
| Robert E. | Strahorn | American journalist. |
| Ada | Ware | One of May's acquaintances. |
| Euphemia | Washington | May's new friend. Aka: Phemie. |
| Narcissa | White | An evangelist. |
| Miss | Williams | A dance teacher. |
| Walter | Woods | A banker. |
| Abigail | | Lieutenant James' wife. |
| Alights on the Clouds | | A prominent Chief of the southern Cheyennes. |
| Antelope Bowes Moving | | An old medicine man. |
| Appleton | | An agent. |
| Bad Horse | | Reverend Hare's acquainance. |
| Bear Sings Woman | | Bad Horse's wife. |
| Black Coyote | | A brash young warrior. |
| Black Man | | One who choses Phemie. |
| Blackbird | | Gerlie's boyfriend. |
| Bloody Foot | | Daisy's husband. |
| Bridge Girl | | Dog Woman's apprentice. |
| Bruyere | | A camp interpreter. |
| Buffalo Calf Road Woman | | Phemie's new friend. |
| Carter | | An agent. |
| Crazy Horse | | One of Sioux's leaders. |
| Crazy Mule | | One of the heads of the state. |
| Crooked Nose | | An old tipi crone. |
| Dodd | | Christian name of Martha's son. |
| Dog Woman | | Reverend Hare's tent mate. |
| Dull Knife | | One of the heads of the state. |
| Feather on Head | | Chief Little Wolf's second wife. |
| Franz | | A hospital attendant. |
| Harold Wild Plums | | Grandson of May Dodd Little Wolf. |
| Hog | | A famous Cheyenne warrior who
chooses Helen. |
| Horse Boy | | The boy who tends to May's horse. |
| Hortense 1 | | One of May Dodd's children. |
| Hortense 2 | | May Dodd's older sister. |
| Howling Woman | | Jules Seminole's wife. |
| Hump | | The Sioux's chief. |
| Jimmy | | May's new friend. |
| Last Bull | | Kit Fox's leader. |
| Little Wolf | | The Chief of the Northern Cheyenne. |
| LittleBat | | An interpreter. |
| May Swallow Wild Plums | | Harold's granddaughter. |
| No Brain | | Gretchen's husband. |
| One Bear | | Runs from Crow's younger brother |
| Pretty Walker | | The Chief's daughter. |
| Quiet One | | The Chief's first wife. |
| Red Cloud | | The owner of the Red Cloud's agency. |
| Runs from Crow | | Marie Blanche's husband. |
| Sara 2 | | Gretchen's daughter. |
| Sitting Bull | | One of Sioux's leaders. |
| Soldier | | May's horse. |
| Stares at Sun | | Black Coyote's rival. |
| Tangle Hair | | A distinguished warrior who
chooses Martha. |
| Tangle Hair Jr. | | Martha's son. |
| Turkey Legs | | One who chooses Narcissa White. |
| Walking Whirlwind | | White Bull's acquaintance. |
| Watkins | | The inspector of the Indian Bureau. |
| Wesley | | Daisy's son. |
| Whipple | | A bishop. |
| Whistling Elk | | Ada Ware's husband. Aka: Stinking Flesh. |
| White Bull | | A medicine man. |
| Wild Plums | | Feather on Head's second husband. |
| William | | One of May Dodd's children. Aka: Willie. |
| Willie | | Feather on Head's son. |
| Woman who moves against the Wind | | Little Wolf's adviser. |
| Wren | | May's daughter. |
| Yellow Wolf | | One who chooses Sara 1. |
