| Mrs. | Anthony | The principal. |
| Connor | bates | The big kid. One of the whiz kids. |
| Mrs. | Billups | Melody's grade 3 teacher. |
| Chuck | Brooks | Melody's father. |
| Melody | Brooks | Born with cerebral palsy. Protagonist. |
| Mrs. | Brooks | Melody's mother. |
| Penny | Brooks | Melody's sister. |
| Aster | Cheng | Melody's schoolmate. |
| Mr. | Dimming | Melody's history teacher. |
| Amanda | Firestone | One of the whiz kids. |
| Miss | Gordon | The regular grade 5 teacher. |
| Mr. | Gross | Melody's grade 1 teacher. |
| Dr. | Hugely | Melody's doctor. |
| Diane | Hyatt | The kindergarten teacher. |
| Charles | Kingsley | The moderator. |
| Mrs. | Lovelace | One of Melody's teachers. |
| Rodney | Mosul | Freddy's friend. One of the whiz kids. |
| Molly | North | One of the whiz kids. |
| Elizabeth | Ochoa | A reporter at Channel Six News. |
| Elena | Rodriguez | One of the whiz kids. |
| Mrs. | Shannon | Melody's new teacher. |
| Mrs. | Tracy | Melody's grade 2 teacher. |
| Violet | Valencia | Melody's neighbor and babysitter. |
| Willy | Williams | One of Melody's disabled classmates. |
| Claire | Wilson | Molly's friend. One of the whiz kids. |
| Ashley | | Melody's group mate. |
| Butterscotch | | Melody's dog. |
| Carl | | One of Melody's disabled classmates. |
| Catherine | | Melody's new aide. |
| Doodle | | Penny's toy. |
| Elizabeth | | Melody's new classmate. |
| Elvira | | Melody's medi-talker. |
| Freddy | | Melody's classmate who uses an electric wheel chair. |
| Gloria | | One of Melody's disabled classmates. |
| Jessica | | Elizabeth's best friend. |
| Jill | | Melody's grade 1 classmate. |
| Maria | | One of Melody's disabled classmates. |
| Ollie | | Melody's goldfish. |
| Paul | | The stage manager. |
| Rose | | Melody's friend. |
| Rusty | | Paul's disabled son. |
