| Dr. |
Ball | Emergency doctor |
| Lucy |
Baughman | Scarlett's twin sister |
| Scarlett |
Baughman | Bernard's neighbor |
| Helen |
Cain | Nena's friend |
| Doreen |
Clark | Bernadette's great-grandmother |
| Charles |
Darwin | Naturalist (reference) |
| Dorothy |
Day | American journalist (reference) |
| Eugene |
Debs | Labor leader (reference) |
| Nena |
DeMatteo | Woman from Father Sullivan's former parish |
| Bernadette |
Doyle | Bernard's wife, deceased |
| Bernard |
Doyle | Former mayor of Boston |
| Natalie |
Doyle | Sullivan's biological mother, Bernard's first wife |
| Sullivan |
Doyle | Bernard's biological son |
| Teddy |
Doyle | Bernard's African-American adoptive son |
| Tip |
Doyle | Bernard's African-American adoptive son. Aka: Thomas O'Neill-Doyle |
| Michael |
Dukakis | Politician (reference) |
| Michael |
Furey | Character in The Dead (reference) |
| Jesse |
Jackson | Civil rights leader (reference) |
| Bobby |
Kennedy | Politician (reference) |
| Martin |
King | Civil rights leader. Aka: Martin Luther King Jr. (reference) |
| Miss |
LaPiana | Kenya's teacher |
| Carl |
Linnaeus | Swedish biologist (reference) |
| Billy |
Lovell | Doreen's husband |
| Loretta |
Lovell | Bernadette's grandmother |
| Mr. |
Morris | Kenya's math teacher |
| Kenya |
Moser | Tennessee's daughter |
| Tennessee |
Moser | Kenya's mother, woman who saves Tip. Aka: Tennessee Alice Moser |
| Wilma |
Rudolph | Athlete (reference) |
| Lawrence |
Simons | Bernard's friend, professor at Kennedy School |
| John |
Sullivan | Priest, Bernadette's uncle |
| Dr. |
Zhang | Physician |
| Claire |
| Nun |
| Ebee |
| Tennessee's ex-boyfriend |
| Kilkelly |
| Drunk who interacts with Doyle |
| Paul |
| Apostle (reference) |
| Ramona |
| Teddy's ex-girlfriend |
| Sally |
| Nurse |
| Thoreau |
| Philosopher (reference) |
