| Kate | Adamala | A synthetic biologist. |
| Eleanor | Arroway | The main protagonist in Contact. AKA: Ellie. |
| Louise | Banks | A linguist. |
| Steven | Benner | A pioneer in the field of synthetic biology. |
| Linda | Billings | NASA consultant and social scientist. |
| Sue | Burke | The author of Semiosis. |
| Octavia | Butler | The author of Dawn. |
| Morgan | Cable | A planetary scientist. |
| Ted | Chiang | A writer. |
| Noam | Chomsky | A linguist. |
| Jessie | Christiansen | The science lead at the NASA Exoplanet archive. |
| Simon | Conway-Morris | A leading voice for convergence. |
| Lee | Cronin | Walker's collaborator. |
| Beverly | Crusher | The ship's doctor. |
| Lt. Commander | Data | The android crew member. |
| Kathryn | Denning | An anthropologist and archaeologist. |
| Steven | Dick | A historian of science. |
| Gary | Donnelly | A physicist. Banks's partner. |
| Frank | Drake | A pioneer in the field of SETI. |
| Ann | Druyan | Carl Sagan's wife. |
| Freeman | Dyson | The physicist, mathematician, and general polymath. |
| Jerry | Ehman | An astronomer. |
| Loren | Eiseley | A nature writer. |
| Mick | Ellison | A visual artist. |
| David | Eterson | A language inventor in movies. |
| Jessica | Fitzpatrick | A critic. |
| Camile | Flammarion | An astronomer. |
| Adam | Frank | An astrophysicist. |
| Galileo | Galilei | An inventor. |
| Francis | Godwin | An English bishop. |
| Stephen Jay | Gould | A paleontologist. |
| Harvey | Greenberg | A psychoanalyst. |
| Karl | Guthke | Scholar of culture. |
| J.B.S | Haldane | A geneticist. |
| Stephen | Hawking | A famous author. |
| Rachel | Heywood-Ferreira | A science fiction scholar. |
| Robert | Hurt | Jessie's collaborator. |
| Christiaan | Huygens | An astronomer. |
| Nikolai | Kardashev | An astronomer. |
| Kris | Kelvin | The protagonist in Solaris. |
| David | Kipping | An astronomer. |
| Nick | Lane | A biochemist. |
| Kurd | Lasswitz | A science writer. |
| Stanislaw | Lem | The author of Solaris. |
| Jonathan | Losos | An evolutionary biologist. |
| Mary | Malone | An astrophysicist. |
| Alec | Marantz | A linguist. Chomsk's colleague. |
| Lynn | Margulis | An evolutionary biologist. |
| William | Martin | An evolutionary biologist and chemist. |
| Abel | Mendez | Professors of physics and astrobiologyy. |
| Lisa | Messeri | An anthropologist. |
| Stanley | Miller | A chemist. |
| Marvin | Minsky | A computer scientist and AI pioneer. |
| Andrea | Moro | A linguist. |
| Kamila | Muchowska | A chemist. |
| Meg | Murry | The protagonist in A Wrinkle In Time. |
| Thomas | Nagel | An essayist. |
| Mohamed | Noor | An evolutionary biologist. |
| Enric | Palle | An astronomer. |
| Louis | Pasteur | A theorist. |
| Tim | Pyle | Jessie's collaborator. |
| Diana | Reiss | The director at Dolphin Research Center. |
| Gene | Roddenberry | The socialist utopia. |
| Mike | Rusell | A biologist. |
| Mary Doria | Russell | An anthropologist. |
| Carl | Sagan | An astronomer. |
| Emilio | Sandoz | A priest and linguist. |
| Caleb | Scharf | An astronomer. Head of Columbia University astrobiology program. |
| Sarah | Scoles | A science journalist. |
| Seth | Shostak | Senior astronomer at SETI. |
| Andrew | Siemeon | The director of the Berkeley SETI research center. |
| Katie | Silvensky | Paleontologist, Author, and Science Educator. |
| Olaf | Stapledon | The author of Star Maker. |
| Jill | Tarter | The SETI scientist. |
| John | Traphagan | An anthropologist. |
| Vernon | Vinge | A science fiction author. |
| Sara Imari | Walker | Adamala's collaborator. |
| Jason | Wright | An astrophysicist. |
| Shelley | Wright | An astronomer. |
| Alfa 177 | | An alien in Star Trek. |
| Aristarchus | | The Greek Philosopher. |
| Askama | | A character in The Sparrow. |
| Copernicus | | A scientist. |
| Emilio | | A character in The Sparrow. |
| Horta | | The silicon-based aliens. |
| Kaltenegger | | The Gaia Data. |
| La Forge | | The commander at Star Trek. |
| Lilith | | The human protagonist in Dawn. |
| Picard | | The captain at Star Trek. |
| Ravna | | A human protagonist in Zones of Thought. |
| Stevland | | The protagonist in Semiosis. |
| Xenomorph | | A disturbing alien from the film "Aliens". |
