| 1 | Ellen | Wharton | An interior designer. |
| | Grace | Madison | Ellen's mother. |
| | George | Wharton | Ellen's husband. |
| | Mireille | | Ellen's close friend. |
| | Brit | | Mireille's husband. |
| | Charles | Williams | An investment banker. |
| | Nigel | | Gina's live-in-partner. |
| | Lydia | | Charles's daughter. |
| | Chloe | | Lydia's sister. |
| | Gina | | Charles's ex-wife. |
| 2 | Juliette | | A resident and ER doctor. |
| | Will | Halter | The chief resident. |
| | Michaela | Mancini | The head nurse. |
| | Mr. | Andrews | A ninety-year-old man who had a broken hip. |
| | Johnny | | A patient. |
| | Dobie | | Johnny's dog. |
| 3 | Robert | Wells | A writer. Aka: Bob. |
| | Peter | Holbrook | A junior student at NYU. |
| | Ben | Weiss | Peter's best friend. |
| | Mike | | Ben's dog. |
| | Anna | | Ben's childhood friend. |
| 4 | Sean | Kelly | Worked at the Office of Emergency Services. |
| | Jane | Holbrook | Peter's mother. |
| 5 | James | Aldrich | Bob's friend. A literary agent. Aka: Jim. |
| 6 | Jake | | Ben's father. |
| | Sarah | Weiss | Jake's wife. |
| | Adam | | Ben's younger brother. |
| | John | Holbrook | Peter's father. |
| | Elizabeth | | Anna's mother. |
| 7 | Phillippa | | Ellen's senior assistant. |
| 9 | Freddy | Harper | George's friend. |
| | Annabelle | | George's girlfriend. |
| 11 | Alice | Maguire | Ellen's assistant in New York. |
| 15 | Gwen | Jones | A therapist. |
