1 | Zoe | Morgan | Rose's older sister. |
| Rose | Morgan | Diagnosed with leukemia at the age of three. |
| Beth | | Zoe and Rose's mother. |
| Brad | | Zoe and Rose's father. |
| Ollie | | The mouse in Brad's book. |
| Marina | | Ollie's wife. |
| Charlie | | One of Marina and Ollie's children. |
| Seraphina | | One of Marina and Ollie's children. |
| Pinkie | | Rose's teddy bear. |
| Pam | | Brad's former therapist and new wife. |
| Christopher | | Zoe's half-brother. |
| Ashley | | Zoe's half-sister. |
| Austin | Roberts | Child advocacy lawyer. |
| Constance | Roberts | Austin's mother. Aka: Connie. |
| Hank | | Beth's boyfriend. |
| Jaime Rose | Roberts | Zoe and Austin's daughter. |
2 | Cathy | Clark | Jaime's pediatrician. |
| | | SIDS - sudden infant death syndrome |
| Amelia | | Austin's oldest brother's wife. |
4 | Jamala | | Jaime's nanny. |
| | Johnsons | Jamala's former employer. |
| Fiona | | Jaime's new nanny. |
| George | | Constance's husband. |
7 | Seth | | Constance's grandson. |
8 | | | ADHD - Attention-Deficit/Hyperactivity Disorder |
9 | Mrs. | Ellis | Jaime's teacher. |
| Mr. | Bob | Teaching assistant. |
| Dr. | Parker | Ear, nose and throat specialist. |
10 | Molly | | George's dog. |
| Patrick | | Constance's grandson. |
13 | Jane | Yamaguchi | Plastic surgeon. |
| Paul | Anders | Psychiatrist. |
16 | Dan | Knoll | Child Protective Services investigator. Aka: Big Red. |
| Pat | Fitzgerald | Dan's former coach. |
| Yvette | | Dan's boss. |