| Bree | Asher | Norah's sister. |
| Norah | Asher-Henry | David's wife. |
| Dr. | Bentley | David's colleague. An obstetrician. |
| Daniel | Birkenhoff | A boy who climbed in an old refrigerator and suffocated to death. |
| Ruby | Centers | The hospital's receptionist. |
| Emelda | Dean | Rupert's wife. Deceased. |
| Rupert | Dean | One of the patient who has pneumonia. Caroline's former patient. |
| Randy | Delaney | Paul's schoolmate. |
| Mr. | Ferry | A neighbor of the Henrys. |
| Caroline L. | Gill | David's nurse. The woman who raised Phoebe. |
| David | H. McCallister | Norah's husband. |
| June | Henry | David's sister. Deceased. |
| Paul | Henry | Phoebe's twin. David and Norah's son. |
| Phoebe G. | Henry-Gill | David and Norah's daughter who has down syndrome. Paul's twin. |
| Ed | Jones | Bree's surgeon. David's colleague. |
| Lauren | Lobeglio | Paul's lover. |
| Duke | Madison | Paul's friend. |
| Dorothy | March | Caroline's boss. A PhD in Physics. |
| Leonard | March | Doro's father. Caroline's patient. |
| Elizabeth | Marshall | Kay's daughter. |
| Flora | Marshall | Norah's friend. |
| Kay | Marshall | Norah's friend who's having a baby girl. |
| Lucy | Martin | Caroline's gossiping neighbor. |
| Janet | Masters | Sylvia's former workmate. |
| Mrs. | Michael | Norah's former neighbor. |
| Mark | Miller | David's guitar instructor. |
| Mrs. | O'Neil | Caroline's friend. |
| Sylvia | Patterson | A woman Caroline is supposed to meet. |
| Mrs. | Pool | A neighbor of the Henrys. |
| Neil | Seimms | The personel manager from IBM. |
| Albert | Simpson | Caroline's husband. Aka: Al. |
| Sharon | Smith | David's new nurse. |
| Ruth | Starling | Norah's friend. |
| Ned | Stone | Paul's schoolmate. |
| Ron | Stone | The lawyer at Upside Down Society. |
| Avery | Swan | Caroline's 8-year-old neighbor. Phoebe's friend. |
| Sue | Wallis | Rosemary's aunt. |
| Stuart | Wells | A respiratory therapist. A man who was in love with Rosemary. |
| Alejandra | | Paul's friend. An organist. |
| Ben | | Bree's lover. |
| Carl | | Colleen's son who has down syndrome. |
| Colleen | | One of the mothers who bore a child with down syndrome. |
| Danny | | Duke's cousin. |
| Frederic | | Norah's lover. |
| Howard | | A former army photographer. David and Norah's new friend. |
| Jack | | Rosemary's son. |
| Jean | | The clerk at The Wolf Wile store where Noah and David met. |
| Jeff | | A man Bree's dating. |
| Lee | | The visiting critic in residence. |
| Linda | | The facility director. |
| Max | | Phoebe's co-worker. |
| Michelle | | Paul's girlfriend. |
| Mike | | Phoebe's friend. |
| Rain | | Phoebe's cat. |
| Robert | | Phoebe's boyfriend. Has down syndrome. |
| Rose | | Rosemary's grandmother. |
| Rosemary | | A young woman who lives in David's old house. |
| Sally | | Norah's friend. |
| Sam | | An investment analyst. Norah's lover. |
| Sandra | | Caroline's companion. A school teacher. |
| Tim | | Sandra's son who has down syndrome. |
| Trace | | Doro's lover. |
