| | | | Part 1 |
| | Roosevelt | Walsh-Adams | Claude's brother. Aka: Roo. |
| | Ben | Walsh-Adams | Roo's brother. |
| | Rigel | Walsh-Adams | Claude's brother. Orion's twin. |
| | Orion | Walsh-Adams | Rigel's twin. Claude's brother. |
| | Claude | Walsh-Adams | Rosie and Penn's gay son. |
| | Penn | Adams | The Adams's father. |
| | Rosalind | Walsh-Adams | Penn's wife. The Adams's mother. Aka: Rosie. |
| | Heather | | Rosie's neighbor. |
| | Jupiter | | The Adams's puppy. |
| | Poppy | | Rosie's little sister. |
| | Taya | | Claude's friend. |
| | Pia | | Claude's friend. |
| | Annlee | | Claude's friend. |
| | Ms. | Danielle | Claude's teacher. |
| | Ms. | Terese | Claude's teacher. |
| | Carmelo | Walsh | Rosie's mother. |
| | Rebecca | Appleton | A kindergarten teacher. |
| | Dwight | Harmon | The school principal. |
| | Mr. | Tongo | The hospital's handyman. |
| | Frieda | | Rigel and Orion's friend. |
| | Victoria | Revels | A district representative. |
| | Grumwald | | A fictional character in Claude's story. |
| | Princess | Stephanie | A fictional character in Claude's story. |
| | Davis | | One of Claude's classmates. |
| | Susan | | One of Claude's classmates. |
| | Carrie | | One of Claude's classmates. |
| | Marybeth | | One of Claude's classmates. |
| | Jason | | One of Claude's classmates. |
| | Lloyd | | Grumwald's study partner. |
| | Nick | Calcutti Sr. | Nicky's father. Cindy's ex-husband. |
| | Cindy | Calcutti | Nicky's mother. |
| | Nicky | Calcutti | Claude's friend. |
| | Anna | Gravitz | A nurse. |
| | Jane | Doe | A transgender. |
| | Chad | Perry | The man Jane met. |
| | | | Part 2 |
| | Aggie | | Claude's friend. |
| | Natalie | | Claude's friend. |
| | Kim | | Claude's secret Santa and friend. |
| | Alice | | Claude's bear. |
| | Miss | Marple | Claude's sheep. |
| | Oscar | | The boy Aggie likes. |
| | Mattie | | The boy Mattie and Kim likes. |
| | Chester | | The new boy from Claude's neighborhood. |
| | Marginny | Granderson | Rosie's new friend. Aggie's mother. |
| | Frank | Granderson | Marginny's husband. |
| | Cayenne | Granderson | Aggie's sister. |
| | Roverella | | The Granderson's chihuahua. |
| | Mr. | Menendez | Claude's principal. |
| | Mrs. | Wonks | Rosie's patient. |
| | Howie | | Rosie's co-physician. |
| | James | | Rosie's co-physician. |
| | Yvonne | | The owner of Rosie's clinic. |
| | Derek | McGuinness | Roo's enemy. |
| | Mrs. | Birkus | Roo's teacher. |
| | Harry | Eliott | One of the Adams's neighbors. |
| | Mark | | Harry's iguana. |
| | Mr. | Mohan | One of Claude's teachers. |
| | Marnie | Alison | One of Claude's schoolmates. |
| | Keith | Rice | Aggie's friend. |
| | Josh | Edison | Claude's math classmate. |
| | | | Part 3 |
| | Ling | | Claude's guide. |
| | Sorry | Ralph | K's ambulance. |
| | Mrs. | K | Rosie's colleague in Thailand. Aka: Kathoey. |
| | Mya | | One of Claude's students. |
| | Zeya | | One of Claude's students. |
| | Dao | | One of Claude's students. |
| | Naw | Ga | The school principal/teacher and mayor. |
| | Steph | | One of Claude's friends. |
| | Nok | | Claude's tour guide. |
