| 1 | Isabella | Stone | Protagonist. Aka: Izzy. |
| | Joyce | Stone | Izzy's mother. Deceased. |
| | Peg | Barrows | The museum curator. Izzy's foster mother. |
| | Mary | Rote | The first patient of Willard Asylum. |
| | Harry | Barrows | The Art Director of the State Museum. Izzy's foster father. |
| 2 | Bella Clara E. | Cartwright | One of the protagonists. |
| | William | Cartwright | Clara's older brother. Deceased. |
| | Henry Earl | Cartwright | Clara's father. |
| | Ruth | Cartwright | Clara's mother. |
| | Julia | | Clara's friend. |
| | Mary | | Clara's friend. |
| | Lillian | | Clara's friend. |
| | Bruno | Moretti | Son of a shoemaker. Clara's boyfriend. Aka: Joseph Russo. |
| | Joe | | The drunkard who kissed Clara. |
| | Richard | Gallagher | Henry's business partner. |
| | James | Gallagher | Clara's fiancé. |
| 3 | Mr. | Hudson | Izzy's teacher. |
| | Ethan | Black | Izzy's friend and classmate. Aka: Raven Boy. |
| | Luke | Anderson | One of Izzy's classmates. |
| | Shannon | MacKenzie | Ethan's girlfriend. |
| | Crystal | | Shannon's friend. |
| | Alexandra | | Izzy's new friend. Aka: Alex. |
| | Dave | | Shannon's friend. |
| 4 | Dr. | Thorn | Clara's doctor. |
| | McCarn | | Clara's nurse. |
| | Yott | | McCarn's co-nurse. |
| | Mr. | Glen | The man who took Clara to Willard Asylum. |
| 5 | Peter | Black | Peg and Harry's friend. Ethan's father. |
| | Lucy | | Ethan's dog. |
| 6 | Dr. | Roach | The doctor at Willard Asylum. |
| | Rita | Trench | One of the nurses at Willard Asylum. |
| 9 | Mr. | Defoe | Ethan and Izzy's teacher. |
| 10 | Dan | | The orderlies in charge at Willard. |
| | Richard | | The orderlies in charge at Willard. |
| | Stanley | | Clara's co-patient. Stanford. |
| | Esther | | Clara's co-patient. |
| | Madeline | | Clara's co-patient. |
| | Lawrence | Lawrence | The grave digger at Willard. |
| 13 | Beatrice E. | Moretti | Clara and Bruno's daughter. |
| | Dr. | Slade | Clara's ob-gyne. |
| | Miss | Mason | The woman from Children's Aid Society. |
| 14 | Kim | | Alex's friend. |
| | Fin | | Alex's friend. |
| | Jackie | | Alex's friend. |
| | Dave | | Ethan and Izzy's classmate. |
| | Bryan | | Ethan and Izzy's classmate. |
| | Paul | | Ethan and Izzy's classmate. |
| 16 | Matilda | | The old laundry woman. |
| 23 | Renee | | Rita's nurse. |
