| | | | Part 1 |
| | Bruce | Adler | Jane's husband. |
| | Jane | Adler | Bruce's wife. |
| | Eddie | Adler | Bruce and Jane's son. |
| | Jordan | Adler | Bruce and Jane's son. |
| | Crispin | Cox | The man in the wheelchair. One of the plane passengers. |
| | Linda | Stollen | X-ray technician. One of the plane passengers. |
| | Benjamin | Stillman | A soldier. One of the plane passengers. |
| | Mark | Lassio | A writer. One of the plane passengers. |
| | Florida | | Linda's seatmate aboard the airplane. |
| | Veronica | | The chief flight attendant. |
| | Ellen | | A flight attendant. |
| | Luis | | A flight attendant. |
| | Donovan | | The detective-in-charge. |
| | Lacey | Curtis | Jane Adler's sister. Edward's aunt. |
| | John | Curtis | Lacey's husband. |
| | Susan | | The head of public relations at Denver Hospital. |
| | Bobby | Stollen | Linda's husband. |
| | Louisa | Cox | Crispin's first wife. |
| | Gary | | Linda's girlfriend. |
| | Besa | | Shay's mother. |
| | Shay | | Edward's new friend. Besa's daughter. |
| | Mahira | | Jordan's lover. |
| | Lolly | | Benjamin's grandmother. |
| | Gavin | | Benjamin's colleague. |
| | Dr. | Mike | Edward's therapist. |
| | Arundhi | | The school principal. |
| | | | Part 2 |
| | Dr. Nancy | Louis | The doctor who died at the plane crash. |
| | Lionel | | Veronica's ex-boyfriend. |
| | Mrs. | Tuhane | The gym teacher. |
| | Margaret | | Edward's schoolmate. |
| | Samuels | | Crispin and Louisa's lawyer. |
| | Jax | Lassio | Mark's brother. |
| | Beezus | | Nancy's cat. |
| | Jeannette | Louis | Nancy's mother. |
| | Harrison | Cox | Crispin's son. |
| | Madame | Victory | A tarot card reader. |
| | Tahiti | | The man who wrote to Edward about Jax's death. |
| | | | TOGA - Take off and go around. |
| | Lyle | | A former volunteer paramedic. |
| | Olivia | | Lyle's co-paramedic. |
| | Bob | | Lyle's co-paramedic. |
