1. The novel begins with Jojo’s thoughts, "I like to think I know what death is" and "I want Pop to know I can get bloody" (page 1). How do these thoughts set the stage for Jojo’s birthday and what follows?

2. How does Given’s death shape Leonie, Pop, and Mam? How does it change how they relate to each other?

3. Why does Given begin appearing to Leonie after Michael goes to jail, whenever she gets high? Why doesn’t Leonie tell anyone about seeing Given?

4. Leonie says from the first moment she saw Michael, he "saw me.… Saw the walking wound I was and came to be my balm" (page 54). Discuss how guilt, desire, taboo, defiance, and grief are at work in Michael and Leonie’s connection to each other.

5. What does Leonie get out of her friendship with Misty? What does Jojo see in the dynamics at play between Misty and Leonie?

6. Discuss the gris-gris bag from Pop that Jojo finds hidden in his clothes (page 63). What does each item signify? Why must Jojo hide it from Leonie?

7. Why can Pop only tell Richie’s story to Jojo in pieces (page 70)? What do you think Pop wants or needs Jojo to understand?

8. As Leonie looks at Jojo and Kayla in the back seat on their way to pick up Michael, she thinks, "Sometimes, when Jojo’s playing with Kayla or sitting in Mama’s room rubbing her hands or helping her turn over in the bed, I look at him and see a hungry girl" (page 95). Why does Leonie see this "hungry girl" in Jojo?

9. Why is Jojo convinced that "Leonie kill things" (page 108)? Why are Leonie and Jojo always in conflict, especially concerning how to take care of Kayla?

10. When Richie joins Jojo at Parchman, is it a surprise? Why is Richie tied to Parchman? And to River?

11. Why does Michael brawl with Big Joseph and ultimately choose to leave with Leonie rather than stay with his parents (page 208)?

12. When Mam insists that Leonie help her die, to "Let me leave with something of myself" (page 216), what makes Leonie hesitate? Why does she wish for Given to be there in that moment?

13. What does Richie mean when he tells Jojo, "I can’t. Come inside. I tried. Yesterday. There has to be some need, some lack. Like a keyhole. Makes it so I can come in. But after all that — your mam, your uncle. Your mama. I can’t. You’ve…changed. Ain’t no need. Or at least, ain’t no need big enough for a key"? (page 281)

14. Water plays an important role throughout the novel. Pop’s name is River. Mam is known as the "saltwater woman." The town and prison where Pop and Michael are incarcerated are named for the "parched man." Jojo wonders who the parched man is, if he looked like Pop, Jojo, or Michael. Which characters seem to need water? Which are of the water?

15. Kayla is central to the final scene of the novel, with the "tree of ghosts." Jojo describes her: "Her eyes Michael’s, her nose Leonie’s, the set of her shoulders Pop’s, and the way she looks upward, like she is measuring the tree, all Mam. But something about the way she stands, the way she takes all the pieces of everybody and holds them together, is all her. Kayla" (page 284). How is it fitting that Kayla closes the story, telling the ghosts to "Go home" and singing to them and to Jojo?