| 1 | Tina |
| One of the vet technicians |
| | Maggie |
| One of the vet technicians |
| | Xavier |
Rush | A veterinarian |
| | Samantha |
Diaz | A social media manager. Aka: Sam |
| 2 | Jeneva |
| Samantha's sister |
| | Pooter |
| A cat |
| 3 | Chris |
| One of Xavier's best friends |
| | Mike |
| One of Xavier's best friends |
| | Jesse |
| One of Xavier's best friends |
| | Becca |
| One of Xavier's best friends |
| | Rhysand |
| Initially presented as a handsome but arrogant "bad boy" villain |
| 4 | Braden |
| One of Samantha's nephews |
| | Holden |
| One of Samantha's nephews |
| | Chris |
Hemsworth | Australian actor |
| | Carolyn |
| Xavier's last girlfriend |
| | Oscar |
| Samantha's ex-boyfriend |
| | Peanuts |
| A dog |
| | Elizardbeth |
| A lizard |
| | John |
Wick | American media franchise character |
| 5 | Jake |
| Xavier's dog |
| 7 | Winnie |
| Xavier's dog |
| | Ginger |
| Samantha's first pet |
| | Hambert |
| A hamster |
| 12 |
Lisa | |
Samantha's mother |
| | Elizabeth |
Arden | Canadian-American businesswoman, founder of Elizabeth Arden, Inc. |
| | Tristan |
| Samantha's brother |
| | Ned |
| A bartender |
| | Lord |
Farquaad | Movie character (Shrek) |
| | Alexa |
| Voice assistant AI |
| | Billy |
Joel | American singer-songwriter and pianist |
| 14 |
Ronald | Reagan |
40th U.S. President |
| 20 |
Dan | |
Samantha's father |
| 21 |
Brad | |
One of Xavier's dogs |
| | Gary |
| One of Xavier's dogs |
| 23 |
Veronica | |
Tina's friend |
| 26 |
Donna | |
Mike's mother |
| | Janessa |
| Mike's younger sister |
| | Shannon |
Horwedel | Samantha's childhood bully |
| 28 |
Jafar | |
An African gray parrot |
| 29 |
Jon | Secada |
Cuban-American singer-songwriter and actor |
| 33 |
Hank | Brekken |
Retired veterinarian, Xavier's mentor |
| 34 |
Pugsly | |
A dog |
| 36 |
Debbie | |
Lisa's cousin |
| | Roman |
| Samantha's uncle |
| 44 |
Claire | |
Dr. Hank's wife |
| 46 |
Apple Bottom | Jeans |
Name given to a tabby cat |
| Epi |
Alanis Nadine | Morissette |
Canadian-American singer-songwriter and musician |
