| | | | Part 1 |
| 1 | Frances Grace | McGrath | Protagonist. AKA: Frankie. |
| | Finley | McGrath | Frankie's older brother. |
| | Bette | McGrath | Frankie's mother. |
| | Francis | McGrath | Frankie's grandfather. |
| | Alexander | | Frankie's grandfather. |
| | Joseph Ryerson | Walsh | Finley's best friend. |
| | Kennedy | | The current President. |
| 2 | Jilly | | The patient's girlfriend. |
| 3 | Connor | McGrath | Frankie's father. |
| 4 | Norm | Bronson | The captain. |
| | Patty | Perkins | A surgical nurse. |
| | Wendy | Goldstein | Frankie's major. |
| 5 | Ethel | Flint | ER Nurse. |
| | Barbara Sue | Johnson | A surgical nurse. Frankie's best friend. AKA: Barb. |
| | Jamie | Callahan | The doctor. Frankie's boss. |
| 6 | Private | Fournette | The dying soldier. |
| | George | | Ethel's boyfriend. |
| 7 | Ted | Smith | The captain. Frankie's superior. |
| | Jorge | Ruiz | One of Frankie's patients. |
| 8 | Trevor | | One of Frankie's patients. |
| | Kaylee | | Jamie's niece. |
| | Sarah | Callahan | Jamie's wife. |
| | Davy | Callahan | Jamie's son. |
| 9 | Mai | | One of Frankie's patients. |
| 10 | Slim | | Ethel's lover. |
| | Rob | Aldean | The new doctor. |
| 11 | Wilma | Cottington | The new nurse. |
| | Sergeant | Alvarez | The officer who accompanies Frankie in Pleiku. |
| | Harry | Dickerson | A Lieutenant Colonel. AKA: Hap. |
| | Winstead | | Frankie's new captain. |
| | Waite | | One of the soldiers. |
| 12 | Will | Johnson | Barb's brother. |
| | Joey | | Barb's uncle. |
| | Coyote | | One of Rye's soldiers. |
| 13 | Albert | Brown | One of Frankie's patients. |
| | Shirley | Brown | Albert's mother. |
| | Sharlene | | The newest nurse in the OR. |
| 15 | Margie | Sloan | Frankie's new hooch mate. |
| | Miniver | | The new chief nurse of the seventy first. |
| 16 | Edgar | LaTour | Rye's superior. |
| 17 | Dr. | Morse | Frankie's boss. |
| | Juan | Martinez | One of the soldiers. |
| | Ryan | Dardis | The new surgeon. AKA: Hollywood. |
| 19 | Paul | | The hairdresser. |
| | Dr. | Brenner | Bette's friend. |
| 20 | Delores | Smart | Director of Nursing. |
| | Mrs. | Henderson | The night charge nurse. |
| | Elena | Garcia | Frankie's patient. |
| | Jose | Garcia | Elena's husband. |
| 21 | Laura | Gillihan | Bette's friend. |
| | Rebecca | Gillihan | Laura's daughter. Frankie's old friend. |
| | Dana | Johnson | Frankie's college friend. |
| | Jeffrey | Heller | Dana's fiance. |
| | Chad | | Becky's husband. |
| 22 | Dr. | Durfee | A psychiatrist. |
| | | | Part 3 |
| 23 | Henry | Acevedo | The man that Frankie met at the anti-war march. |
| 24 | Mike | Jenkins | A prisoner of war. |
| | Anne | Jenkins | Mike's wife. |
| | Jane | Adon | A war widower. |
| | Bob | Dole | The senator. |
| | Karla | | Receptionist. |
| 25 | Rose | Contreras | The receptionist at the league of POW. |
| | Joan | | The girl from the POW. |
| | Charlotte | | Joan's daughter. |
| | Arturo | | Henry's nephew. |
| 26 | William | Calley | The man who responsible for the Lai massacre. |
| | Leo | Stall | Connor's veteran friend. |
| | Walter | Reed | Leo's colleague. |
| | Sussanah | | Deceased. Henry's wife. |
| 27 | Lola | | Massie's assitant. |
| | Dr. | Massie | The OB-GYNE. |
| | Dell | | The anesthesiologist. |
| | Mark | Lundberg | Frankie's boss. A doctor. |
| 29 | Noah | | Ethel's husband. |
| | Cecily | | Ethel's daughter. |
| | Celine | | Bette's dead baby. |
| 30 | Melissa | | Rye's wife. |
| | Joey | | Rye's child. |
| | Geneva | Stone | Frankie's boss. |
| 31 | Phil | | The policeman. |
| | Bill | Brightman | Coronado High Principal. |
| 33 | Natalie | | Henry's new fiance. |
| | Dr. | Alden | Henry's colleague. A psychologist specializing in Vietnam Veterans. |
| 35 | Donna | | Frankie's old colleague. |
| | Gwyn | | One of the girls at the reunion. |
| | Liz | | One of the girls at the reunion. |
| | Ramona | | One of the girls at the reunion. |
| | Finley | McGrath | Henry and Frankie's son. |
| | Frances | Callahan | Jamie's daughter. |
