| 1 | Marge | Slayton | Donald's wife. |
| | Barker | | The Space dog. Aka: Little Curly. |
| | Samuel | Goldwyn | The administrator of NASA. |
| | Malcolm | Carpenter | One of the Nation's Mercury astronauts. |
| | Leroy | Cooper Jr. | One of the Nation's Mercury astronauts. Aka: Gordo. |
| | John | Glenn Jr. | One of the Nation's Mercury astronauts. |
| | Virgil | Grissom | One of the Nation's Mercury astronauts. Aka: Gus. |
| | Walter | Schirra | One of the Nation's Mercury astronauts. Aka: Wally. |
| | Alan | Shepard Jr. | One of the Nation's Mercury astronauts. |
| | Donald | Slayton | Marge's husband. One of the Nation's Mercury astronauts. Aka: Deke. |
| | T. Keith | Glennan | The man who took the podium. |
| | Annie | Glenn | John's wife. |
| | Betty | Grissom | Gus's wife. |
| | Louise | Shepard | Alan's wife. |
| | Rene | Carpenter | Scott's wife. |
| | Scott | Carpenter Jr. | Scott and Rene's son. |
| | Lyndon | Johnson | Senator. |
| | Kent | Slayton | Marge and Deke's son. |
| | Trudy | Cooper | Gordo's wife. A pilot. |
| | Gordo | Cooper | Trudy's husband. An astronaut. |
| | Amelia | Earhart | Founder of the Women's Transcontinental Air Race. |
| | Pancho | Barnes | Owner of a bar on Edward Air Force base. |
| | Hell | Cooper | Gordo's grandmother. |
| | Camala | Keoki | Gordo and Trudy's daughter. |
| | Jo | Schirra | Walter's wife. A Navy royalty. |
| | James | Holloway Jr. | The 4-star Admiral. Jo's step-father. |
| | Richard | Nixon | The U.S. Senator. |
| 2 | Leo | Deorsey | Mercury's astronaut's lawyer. |
| | President | Eisenhower | The U.S. President. |
| | Dr. | Spock | The childcare expert. |
| | Loudon | Wainwright | The Life ghostwriter. |
| | Ralph | Morse | The Life photographer. |
| 3 | John | Powers | NASA's press officer. |
| | Henri | Landwirth | Holiday Inn's manager. |
| | Jim | Rathmann | Owner of Cadillac-Chevrolet dealership. |
| | Julie | Shepard | Louise and Alan's daughter. |
| | Laura | Shepard | Louise and Alan's daughter. |
| | Alice | | Louise's niece. |
| | Mr. | DuPont | A real estate owner. |
| | Polly | Shepard | Alan's sister. |
| | John | Kennedy | The new U.S. President. |
| | Bob | Gilruth | Head of NASA. |
| 4 | Jackie | Kennedy | Socialite and instant celebrity. |
| | Doc | Castor | Annie's father. |
| 5 | Yuri | Gagarin | A cosmonaut. |
| 6 | Bill | Douglas | The NASA's flight surgeon. |
| | Walter | Cronkite | The CBS's reporter. |
| | Eugene | Bodin | The French artist. |
| 7 | Lawrence | Marcus | Scion of the Dallas-based dept. store. |
| | Martin | Schirra | Jo and Wall's son. |
| | Neil | Armstrong | Part of the Nine astronauts. |
| | Frank | Borman | Part of the Nine astronauts. |
| | Charles | Conrad | Part of the Nine astronauts. Aka: Pete. |
| | Jim | Lovell | Part of the Nine astronauts. |
| | Jim | McDivitt | Part of the Nine astronauts. |
| | Elliot | See | Part of the Nine astronauts. |
| | Tom | Stafford | Part of the Nine astronauts. |
| | Ed | White | Part of the Nine astronauts. |
| | John | Young | Part of the Nine astronauts. Gus's partner. |
| | Jane | Conrad | Pete's wife. Aka: Mimi. |
| | Marilyn | Lovell | Jim's wife. |
| | Pat | White | Ed's wife. |
| | Faye | Stafford | Tom's wife. Harriet's best friend. |
| | Susan | Borman | Frank's wife. |
| | Pat | McDivitt | Jim's wife. |
| | Marilyn | See | Eliott's wife. |
| | Barbara | Young | John's wife. |
| | Lady | Bird | The U.S. first lady. |
| 8 | Henry | Fonda | A Hollywood actor. |
| | Nancy | Robbins | A prominent Houston socialite. |
| | Truman | Capote | One of Jane's literary darlings. |
| | Nellie | Connally | The first lady of Texas. |
| | Jacques | Cousteau | An underwater explorer. |
| | Oleg | Cassini | Jackie's designer. |
| | Del | Berry | Dr. Berry's wife. Trudy's best friend. |
| 9 | | | Togethersville - The astronauts' compound. |
| | Gene | Cernan | The astronauts' pilot. Aka: Geno. |
| | | | White Rocket - Gene's T-38 talon jet. |
| | Walt | Cunningham | Gene's colleague. |
| | Sue | Bean | The astronauts' neighbor. |
| | Joan | Aldrin | The astronauts' neighbor. |
| | Roger | Chaffee | One of the astronauts. |
| | Martha | Chaffee | Roger's wife. |
| | Venus | | Gene's cocker spaniel. |
| | Jeanne | Bassett | The astronauts' neighbor. |
| | Edwin | Aldrin | Joan's husband. |
| | Dr. | Rendezvous | The moniker. |
| | Popo | I | Buzz's monkey. |
| 10 | Susy | | John's mistress. |
| | Alexey | Leonov | A cosmonaut. |
| | Dr. | Adels | Marilyn's doctor. |
| | Charles | De Gaulle | The President of France. |
| | MacDuff | | The Lovell's collie. |
| 11 | | | NOW - National Organization for Women. |
| | Mel | Brooks | A producer and director. |
| | Adelin | | Rene's neighbor. |
| | Mike | Collins | One of the astronauts. |
| | Mitchell | Grissom | Gus's mother. |
| | Cecile | Grissom | Gus's father. |
| | Stephen | Chaffee | Roger and Martha's son. |
| | Sheryl Lyn | Chaffee | Roger and Martha's daughter. |
| 12 | Barbara | Cernan | Gene's wife. |
| | Catherine | Marshall | The widow of a chaplain of the U.S. senate. |
| | Dee | O'Hara | The astronauts' nurse. |
| | Janis | Joplin | A famous singer. Marge's friend. |
| | Nanabelle | | Marge's mother. |
| | Gratia | Lousma | A woman who seeks counsel and comfort from Marge. |
| | Clare | Schweickart | Pat's friend. |
| | Rusty | Schweickart | Clare's husband. An astronaut. |
| 13 | Bobby | Kennedy | A Senator. Aka: RFK. |
| | Ethel | Kennedy | Bobby's wife. |
| | Harriet | | Donn's wife. |
| | Donn | Eisele | Harriet's husband. |
| | Dr. Michael | DeBakey | Harriet's friend. |
| | Dodie | Hamblin | The Life's journalist. |
| | Susie | Eisele | Donn's new wife. |
| 14 | | | SCUM - Society for Cutting Up Men. |
| | Valerie | Solahan | A SCUM member who shot Andy Warhol. |
| | Chris | Kraft | The flight director of Apollo 8. |
| 15 | Werner | Von Braun | NASA's German rocket scientist. |
| | Eddie | Rickenbacker | The World War 1 flying ace. |
| | Mrs. | Goddard | Robert Goddard's widow. |
| | Robert | Goddard | A rocket pioneer. |
| | Diaz | Ordaz | The President of Mexico. |
| | Bill | Carpenter | The Apollo 11 flight surgeon. |
| | Dr. | McGuire | Gratia's doctor. |
