| Felix | Argyros | Dex's boss. aka: Fish. |
| Jean-Michel | Basquiat | American artist. |
| Carolyn | Bessette | Wife of John F. Kennedy Jr. |
| Amanda | Burns | Claire's new name. |
| Al | Capone | American gangster. |
| Agent | Castro | A federal DEA officer. |
| Hillary | Clinton | American politician. |
| Marjorie | Cook | A senator. Rory's mother. |
| Rory | Cook | A philanthropist. |
| Bruce | Corcoran | Rory's longtime assistant. |
| Mr. | Cosatino | Eva's neighbor |
| Mrs. | Crespi | A friend of Kelly's mother. |
| Petra | Federotov | Claire's friend. |
| Geraldine | Ferraro | American lawyer and politician. |
| Dr. | FitzGerald | Considered as the Founding Father of Zone Therapy. |
| Charlie | Flanagan | Former senior accountant with the Cook Foundation. |
| Craig | Henderson | A social worker. |
| Erwin | James | Rachel's father |
| Eva | James | Claire's new acquaintance. |
| Rachel Ann | James | Eva's mother. |
| Jasper | Johns | American painter and sculptor. |
| John F. | Kennedy Jr. | President John F. Kennedy's son. |
| Kate | Lane | A political commentator. |
| Maggie | Moretti | Rory's ex-girlfriend. |
| Mrs. | Morris | A government teacher in the twelfth grade. |
| Jacqueline K. | Onassis | Former First Lady of the United States. |
| Anita | Reynolds | The director of the Center Street Literacy. |
| Wade | Robert | Eva's acquaintance. |
| Auguste | Rodin | French sculptor. |
| Donny | Rodriquez | A baseball star. |
| Hillary | Stanton | NTSB Senior Communications Officer. |
| Claire | Taylor | Rory's wife. |
| Bess | | Emily's partner. |
| Brett | | One of Eva's acquaintances. |
| Brittany | | Dex's acquaintance. |
| Carmen | | Eva's adoptive mother. |
| Constance | | A maid. |
| Cressida | | Donny's girlfriend. |
| Danielle | | Claire's secretary. |
| Danny | | Dex's acquaintance. |
| David | | Eva's husband. |
| Dex | | One of Eva's acquaintances. |
| Ellie | | Liz's daughter. |
| Emily | | Liz's closest friend. |
| Gabe | | DuPree's manager. |
| Jacinta | | Kelly's daughter. |
| Jeremy | | One of Eva's best clients. |
| Jim | | One of Claire's colleagues. |
| Joshua | | Norma's son. |
| Kelly | | Claire's new acquaintance. |
| Liz | | Eva's friend. |
| Marcy | | A caterer. |
| Marilyn | | Kelly's mother. |
| Mark | | Carmen's husband. |
| Mary | | Rory's aunt. |
| Maxwell | | Rachel's brother. |
| Mel | | Jacinta's friend. |
| Nancy | | Rachel Ann's mother. |
| Nico | | Petra's brother. |
| Norma | | A chef. |
| Saul | | One of Eva's acquaintances. |
| Sister Bernadette | | The nun who raised Eva. |
| Tom | | Kelly's boss. |
| Vera | | Bess and Emily's department head. |
| Violet | | Claire's sister. |
