| Cardi | B | American rapper. |
| Senora | Batista | Xiomara's mother. Aka: Mami. |
| Xiomara | Batista | A poet. Aka: Xio. |
| Mr. | Bildner | A teacher. |
| J. | Cole | American rapper. |
| Miss | Galiano | English teacher. |
| Chris | Hodges | Member of the poetry club. |
| Kendrick | Lamar | American rapper. |
| Nelson | Mandela | Former president of South Africa. |
| Floyd | Mayweather | Professional boxer. |
| Nicki | Minaj | Rapper. |
| Mira | Muchacha | Mami's favorite sayings to Xiomara's ears. |
| Isabelle P. | Riley | One of the members of the poetry club. |
| Eleanor | Roosevelt | Former First Lady of U.S. |
| Father | Sean | A priest. |
| Mother | Teresa | Honored Saint by the Catholic Church. |
| Kanye | West | American rapper. |
| Stevie | Wonder | American singer-songwriter. |
| Poet | X | Xiomara's stage name. |
| Adam | | A figure in the book of Genesis. |
| Aman | | Xiomara's lab partner. |
| Beyonce | | American singer-songwriter. |
| Caridad | | Xiomara's best friend. |
| Cody | | Xavier's friend. |
| Delilah | | A woman mentioned in the Bible. |
| Drake | | Xiomara's acquaintance. |
| Eve 1 | | Adam's wife. |
| Eve 2 | | One of an old school rappers. |
| Iliana | | Xiomara's acquaintance. |
| Jay Z | | One of an old school rappers. |
| Marcy | | Xiomara's new lab partner. |
| Mary | | Mother of Jesus. |
| Medusa | | A Gorgon. |
| Nas | | One of an old school rappers. |
| Papi | | Xiomara's father. |
| Pops | | Aman's father. |
| Reuben | | Aman's friend. |
| Stephan | | One of the members of the poetry club. |
| Xavier | | Xiomara's twin brother. |
